Founded on August 8, 2011, our company was previously known by the brand Nextomics, and is the first company in China providing third-generation sequencing services. Our certification programmes ensure certified labs offer the highest quality service on our sequencing platforms. Real-time nanopore-based DNA/RNA sequencing technology. The method, known as nanopore sequencing, helps public health bodies to trace rapidly how cases of SARS-CoV-2 infection are linked, triggering timely quarantining of … Roche announced that it is acquiring Genia, a California based sequencing technology startup company. Oxford Nanopore Technologies, developer of the pocket-sized MinION real-time DNA/RNA sequencer and other nanopore analysis devices, last month completed its latest financing of … Oxford Nanopore Technologies (ONT), the sequencing company known for making small and portable nanopore-based sequencing platforms, announced a … Oxford Nanopore Technologies products are currently for research use only. For applied markets, nanopore sequencing is now providing rapid, accurate scientific insights to users in healthcare, agriculture and industry. Nanopore sequencing We believe that inexpensive nanopore sequencing will change the landscape of molecular diagnostics by enabling comprehensive analysis of clinical specimens in a commercially sustainable fashion with field-deployable instrumentation. NorthShore Bio is developing a silicon semiconductor-based molecular detection platform based on a proprietary nanopore technology combining synthetic, solid-state, tunable nanopores for direct single molecule detection and integrated digital output. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Accessible, easy to use and fully scalable for any requirement. In fact, the two companies have been sparring since 2012 after breaking off plans to jointly develop a nanopore instrument and becoming rivals. Nanopore sequencing enables the detection of modified nucleotides, such as methylcytosine, and phasing of reads in parental haplotypes, and based on this we can detect allele-specific epigenetic marks. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Qiagen N.V. "…this study provides a clear example of the use of long-read sequencing in solving undiscovered genetic causes in human diseases. The Nabsys platform uses solid-state nanodetectors to analyze single DNA molecules, revealing both location and identity of DNA sequences over long distances. On the Executive team, he has responsibility for all chemical and biological R&D activity within the company and particularly the design and delivery of the company’s nanopore-based sequencing technology. doi: 10.1128/JCM.00583-20. During an update at the 2020 Nanopore Community Meeting, Oxford Nanopore revealed a number of key advances in its sequencing technology. high-throughput sequencing, Novel Coronavirus (COVID-19): information and You can export these companies to Excel by clicking here. Noblegen Biosciences Inc. is a U.S. company which aims to realize the promise of personalized medicine by moving whole genome sequencing into the clinic. How the NGS (next generation sequencing) benchtop systems will do versus the larger, high throughput systems. The Nanopore sequencer is proven compatible with a variety of input material such as genomic DNA, amplified DNA, cDNA, and RNA. The company’s optical nanopore technology is based on highly differentiated IP exclusively licensed from Harvard University and Boston University. If you any questions about our products or services, chat directly with a member of our sales team. Nanopore sequencing technology is one example of such technologies that can produce long read lengths. The fragmented genomic ends are then repaired and tailed with poly dA using a … Oxford Nanopore was founded in 2005 to exploit stochastic sensing.  |  The versatile, low-cost SBX sequencing technology, with its tremendous value creation potential, will enable opportunities for a vast array of growing markets applications. Oxford Nanopore Technologies (ONT) is the first nanopore sequencing-based company and has generated a lot of excitement over their nanopore platforms like MinION TM, GridION TM, and PromethION TM. On the 2020 Nature Index, Grandomics was ranked second in China’s sequencing industry. How well NGS systems will penetrate into diagnostics. sequenced) at near 100% accuracy. Headquartered in, appropriately enough, Oxford, UK, Oxford Nanopore reported $18.1 million in revenues in 2017. Sequencing By eXpansion (SBX TM ) Stratos Genomics, a Roche company, has developed a novel chemistry called Sequencing by eXpansion (SBX) to significantly improve the accuracy and throughput of nanopore sequencing. Next Generation Sequencing (NGS) solutions. Developing the next generation of antibiotics with novel mechanisms of action. To book a call with one of our sales team please click below; Oxford Nanopore’s goal is to enable the analysis of anything, by anyone, anywhere. Registered Office: Gosling Building, Edmund Halley Road, Oxford Science Park, OX4 4DQ, UK | Registered No. Oxford Nanopore has developed and commercialises a novel generation of DNA/RNA sequencing technology that provides rich data, is fast, accessible and easy to use in … LamPORE Rapid, highly scalable, low-cost COVID-19 detection. Metrichor was founded to offer fully integrated, bespoke, real-time analysis solutions based on scalable, real time nanopore sensing technologies. Search content across the Nanopore Community. Which up and coming nanopore-based technologies will emerge and how will this affect market applications. A conference hosted by Oxford Nanopore Technologies. It combines with a mini-centrifuge, a PCR thermocycler, and a gel electrophoresis box and power supply with blue LED transillumination – small enough to fit into a laptop-sized bag. Oxford Nanopore has built a device for genetic sequencing that uses a technology they refer to as “nanopore sequencing” which is described below: A nanopore is a nano-scale hole. Nanopore sequencing provides an alternative to classical Sanger and next-generation sequencing methods Genomic DNA Sequencing Kit SQK-MAP004 (ONT): contains DNA CS, 2x wash buffer. 05386273 | VAT No 336942382. Here's a look at the top 10 gene sequencing companies by revenue. Nanopore sequencing uses electrophoresis to transport an unknown sample through an orifice of 10 −9 m in diameter. Rapid, highly scalable, low-cost COVID-19 detection. Grandomics is an internationally-renowned pioneer in third-generation sequencing (TGS). Oxford Nanopore Technologies Limited is a UK-based company which is developing and selling nanopore sequencing products (including the portable DNA sequencer, MinION) for the direct, electronic analysis of single molecules. Oxford Nanopore has developed and commercialises a novel generation of DNA/RNA sequencing technology that provides rich data, is fast, accessible and easy to use. Using nanopore gene sequencing technology to develop fast, low-cost, and miniaturized fourth-generation gene sequencing equipment. Oxford Nanopore has developed and commercialises a novel generation of DNA/RNA sequencing technology that provides rich data, is fast, accessible and easy to use in any location. It is South Korea’s largest sequencing company, with a 12% revenue increase from KRW 91.1 billion ($85.3 million) in 2016. Oxford Nanopore is a gene sequencing company that was spun out of the city’s university in 2005 and has its headquarters at the Oxford Science Park. Genia’s mission is to make genetic information universally available. Nanopore companies NanoporeSolutions, Portugal Nanopore, USA, New Mexico NanoporeDx, USA, St Louis Noblegen Biosciences, MA, USA Oxford Nanopore Technologies, UK Quantapore, CA, USA Quantum Biosystems, Japan Shenzhen P&Z Biological Medical Company; China and P&Z Biological Technology, Newark, USA TwoPoreGuys, USA Noblegen Biosciences Inc. is a U.S. company which aims to realize the promise of personalized medicine by moving whole genome sequencing into the clinic. Several companies have proposed nanopore-based se-quencing strategies. Recent years have seen great progresses in third-generation sequencing. Filter results by content type to refine searches and explore areas of interest. Filter results by content type to refine searches and explore areas of interest. The model is being utilised as a platform to discover and develop an internal pipeline of new antibacterial drugs. Here, using raw electric signals of Oxford Nanopore long-read sequencing data, we design DeepMod, a bidirectional recurrent neural network (RNN) with long short-term memory (LSTM) to detect DNA modifications. Nanopore) sequencer which delivers fast, low-cost and point-of-care sequencing. Nonacus was created by a team of highly motivated scientists and sector professionals with experience in translating research into routine diagnostic tools that benefit patients. By developing a true integrated circuit on standard semiconductor process technology, Genia’s sequencing platform enables the use of molecular diagnostics in everyday clinical care. These facilities are filled with highly advanced platforms such as the ONT PromethION 48, the PacBio Sequel II, the MGISEQ2000, and the Bionano Saphyr . Moreover, we have independently developed NextDenovo/NextPolish TGS assembly software, GrandSV/NextSV structural variation analysis software, GrandPathogen microbial and pathogenic detection software, GrandBox genetically inherited disease analysis software, SCAN-seq TGS single cell sequencing technology, Pore-C/Hi-C Next Generation 3D Genome Technology, LAMP-Pore Nanopore SARS-CoV-2 Rapid Detection Technology, and dbSV Human Genome Structural Variation Database. Other nanopore sequencing companies, including ONT (Davies, 2012), Illumina (A Genomeweb Staff Reporter, 2013a), and Genia (Toner, 2012), which has been acquired by Roche (Karow, 2014e), are all devoted to develop their own integrated circuit platforms for multiplexing detection. Locked-down, research-validated devices for applied sequencing applications. http://www.noblegenbio.com/ Oxford Nanopore makes a novel generation of DNA/RNA sequencing technology that provides rich data, is fast, accessible and easy to use. The company’s core team is composed of highly experienced experts in the TGS field, with a Master Degree and PhD proportion of over 50%. Some of the major companies operating in the global nanopore technologies market are Oxford Nanopore Technologies, NorthShore Bio, Nabsys LLC, Electronic BioSciences, Quantapore Inc., Stratos Genomics, Noblegen Biosciences, and other players. Xpandomers encode the sequence information in high signal-to-noise reporters that enable high-fidelity, single molecule sequencing in a low-cost nanopore instrument. Read more, Extract nucleic acid Short-read bisulfite sequencing and long-read PacBio sequencing have inherent limitations to detect DNA modifications. Roche announced that it is acquiring Genia, a California based sequencing technology startup company. Cyclomics uses proprietary DNA adapters (backbones) and enzymes blends to capture ctDNA molecules and circularize them. The company is developing devices based on nanopore sensing, in which an array of nano-scale ‘holes’ are set in an electrically resistant artificial membrane similar to a cell membrane. We are more than 400 people across 8 locations, working to enable the analysis of anything, by anyone, anywhere. The company’s optical nanopore technology is based on highly differentiated IP exclusively licensed from Harvard University and Boston University. The company provides next generation sequencing products under the Life Sciences Solution business segment. Oxford Nanopore Technologies has developed the nanopore-based DNA and RNA sequencing technology. The current MinION Mk1B device only weighs 90 g, measuring only 3.3 × 10.5 × 2.3 cm in size, fitting in the palm of one's hand. The technology is currently being used in 100 countries, by researchers in human, plant, animal, microbiological or environmental genetics, as well as increasingly in applied market applications such as healthcare or food safety...read more. Oxford Nanopore Technologies, the Wheel icon, EPI2ME, Flongle, GridION, Metrichor, MinION, MinIT, MinKNOW, Plongle, PromethION, SmidgION, Ubik and VolTRAX are registered trademarks of Oxford Nanopore Technologies Limited in various countries. Real-time nanopore sequencing delivers comprehensive analysis of clinical research samples, providing rapid insights into infectious disease, cancer research, immunology, reproductive health, and many other areas of biomedical research. 35 articles with Oxford Nanopore Technologies. You must have cookies enabled to login Two Pore Guys (2PG) has developed a handheld, single-molecule sensing platform with the accuracy, precision, and sensitivity of reference lab equipment and sample-in, results-out capability. Oxford Nanopore.....by Woodford Investment Management were among the selling shareholders. The Company’s goal is to disrupt the way that biological analyses are currently performed, and open up new applications that have a profound, positive impact on society – towards an internet of living things. All rights reserved. Oxford Nanopore Technologies (ONT), a University of Oxford spin-out company, is developing technologies designed to meet these needs. Genia is an early stage nanopore sequencing company founded in 2009. Cyclomics is a Dutch startup company founded in 2018 by scientists of the UMC Utrecht. Nanopore sequencing is a third generation approach used in the sequencing of biopolymers- specifically, polynucleotides in the form of DNA or RNA. New commercial platforms from Oxford Nanopore Technologies (ONT) can generate ultra-long reads from single-molecule nucleic acid fragments of kilobases up to megabases, exceeding the limitation of short reads and dependency on template amplification suffered by the previous generation of sequencing technologies. Oxford Nanopore announces £100M ($140M) fundraising. For many years, we have established a sophisticated set of applications for leading TGS platform, featuring four key modules: “genome research services,” “clinical services,” “bioinformatics,” and “advanced manufacturing.” Nearly 7,000 square meters of research service platforms, medical testing laboratories, and GMP production plants have been constructed in cities such as Beijing, Wuhan, and Suzhou. 2020 Oct 14;JCM.00583-20. Finally, each sequencing-read is processed by state of the art bioinformatics and AI platform which leverages the repetitive structure of the concatemers to remove noise and errors thus delivering super-accurate results. Quantapore Incorporated;Quantapore Inc. is a biotechnology company focused on the development of an ultra-low-cost, high-throughput DNA sequencing platform. These involve either: the excision of monomers from the DNA strand and their funneling, one-by-one, through a nanopore (NanoTag sequencing (Genia), Bayley Sequencing (Oxford Nanopore)); or strand sequencing wherein intact DNA is ratcheted through the On the Executive team, he has responsibility for all chemical and biological R&D activity within the company and particularly the design and delivery of the company’s nanopore-based sequencing technology. OXFORD, England--(BUSINESS WIRE)--Oxford Nanopore Technologies Ltd, the company behind the only …