"[54][55], In June 2020, Bloomberg reported that AstraZeneca Plc had made a preliminary approach to Gilead for a potential merger, worth almost $240 billion. Fax: (650) 578-9264. Download Report (Desktop) Download Report (Mobile) Previous Year in Review PDFs. [citation needed], In 2010, the company acquired CGI Pharmaceuticals for $120 million, expanding Gilead's research expertise into kinase biology and chemistry. Sales of Tamiflu almost quadrupled again in 2005, to $161.6m, during which time the share price tripled. ", "Pharma M&A In 2017: The Most Likely Deal Hunters", "Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia", "US pharma giant Gilead uses 'Double Irish' tax loophole", "Patients sue Gilead, saying drug company intentionally delayed safer HIV medicine", "Tenofovir Effect on the Kidneys of HIV-Infected Patients: A Double-Edged Sword? [79], Several class-action lawsuits have been filed against Gilead over allegations that the company deliberately delayed development of antiretroviral drugs based on tenofovir alafenamide fumarate (TAF) in order to maximize profits from previous-generation medications containing tenofovir disoproxil fumarate (TDF). Forbes magazine ranked Gilead its number 4 drug company, citing a market capitalization of US$113 billion and stock appreciation of 100%, and describing their 2011 purchase of Pharmasset for $11 billion as "one of the best pharma acquisitions ever". Its Farnesoid X Receptor (FXR) program used small-molecule FXR agonists in the treatment of liver diseases such as, It bought EpiTherapeutics for $65 million. Corus was developing aztreonam lysine for the treatment of patients with cystic fibrosis who are infected with Pseudomonas aeruginosa. [89] This designation is intended to encourage the development of drugs affecting fewer than 200,000 Americans by granting strengthened and extended legal monopoly rights to the manufacturer, along with waivers on taxes and government fees. Prevention", "200,000 Uninsured Americans to Get Free H.I.V.-Prevention Drugs", "Gilead to Acquire Immuno-Oncology Company Forty Seven for $4.9 Billion", "Gilead to Acquire Forty Seven for $4.9 Billion", "Gilead buys Forty Seven for $4.9 billion to bolster cancer drug pipeline", "Gilead Completes Acquisition of Forty Seven, Inc", "A new pharma king? Gilead Sciences, Inc. /ˈɡɪliəd/, is an American biopharmaceutical company headquartered in Foster City, California that researches, develops and commercializes drugs. Learn how we’re working to deliver lifesaving medicines and support communities to advance global health. [47] In November, the company announced it will acquire Cell Design Labs for up to $567 million, after it indirectly acquired a stake of 12.2% via the Kite Pharma deal. Raylo Chemical was a custom manufacturer of active pharmaceutical ingredients and advanced intermediates for the pharmaceutical and biopharmaceutical industries. Gilead Sciences, Inc. (“Gilead”) (b) Address of the Principal Business Office or, if none, Residence 333 Lakeside Drive, Foster City, California 94404 (c) Citizenship Delaware (d) Title of Class of Securities Common Stock, $0.001 par value per shares (“Common Stock”) (e) CUSIP No. Phone: +1 650 574 3000. Krijg gedetailleerde informatie over het Gilead Sciences Inc (GILD) Aandeel inclusief Prijs, Grafieken, Technische Analyses, Historische gegevens, Gilead Sciences Rapporten en meer. The company’s stock price has collected -4.34% of loss in the last five trading sessions. [83] Gilead's first TAF medication, marketed under the trade name Genvoya, came out in 2015. [94], In June 2020, Gilead announced that the price of remdesivir is set at US$390 per vial for governments of developed countries including the United States and US$520 for private insurance companies in the US. ", "Gilead delayed safer HIV drug to extend monopoly profits, advocates allege", "Gilead Lawsuits: 41 HIV and PrEP Patients File California Personal Injury Case Over Gilead's TDF-Based Drugs", "Activists pounce on $1,000-a-day price for Gilead's hep C wonder drug, Sovaldi", "Gilead's HCV drug sofosbuvir approved by the FDA but accessible for how many? [45], In August 2017, the company announced it would acquire Kite Pharma for $11.9 billion,[46] equating to $180 cash per share, a 29% premium over the closing price of the shares. That same year, Roche announced FDA approval of Tamiflu (oseltamivir) for the treatment of influenza. "[2] Like many startups, Gilead originally leased its space, but in 2004, the company paid $123 million to buy all its headquarters buildings from its landlords. Sentence reads like they intended for drug to be used for PEP; this was not the case. [3], The company focused its early research on making small strands of DNA (oligomers, or more particularly, oligonucleotides) to target specific genetic code sequences – that is, antisense therapy, a form of gene therapy. In February 2011, the company acquired Calistoga Pharmaceuticals for US$375 million ($225 million plus milestone payments). In July 2006, the U.S. Food and Drug Administration (FDA) approved Atripla, a once a day single tablet regimen for HIV, combining Sustiva (efavirenz), a Bristol-Myers Squibb product, and Truvada (emtricitabine and tenofovir disoproxil), a Gilead product.[24][25][26]. [95], In September 2020 following a review of the evidence, the WHO issued guidance not to use remdesivir for people with COVID-19, as there was no good evidence of benefit. Gilead Sciences, Inc. is a research-based biopharmaceutical company focused on the discovery, development, and commercialization of innovative medicines. In the US, for instance, it was launched at $1,000 per pill or $84,000 for the standard 84-day course. Gilead Sciences Statement on State Attorneys General Letter on Remdesivir Annual Report. This transaction helped cement Gilead as the leader in treatment of the hepatitis C virus by giving it control of sofosbuvir (see below). Citation needed; PEP protocol not established years. Gilead later combined Sovaldi with other antivirals in single-pill combinations. [81][82] Gilead intentionally withheld results of clinical trials demonstrating TAF's relative safety and efficacy and shelved TAF-based therapies until 2010, when the Food and Drug Administration approved Gilead's application to patent TAF. The acquisition brings drug candidate CYT387, an orally-administered, once-daily, selective inhibitor of the Janus kinase (JAK) family, specifically JAK1 and JAK2, into Gilead's oncology pipeline. [18], In 2004, Gilead launched Truvada. [77], Gilead's Entospletinib has shown a 90% complete response rate for MLL type AML. About Gilead Sciences . [citation needed], One reason for entering into the Tamiflu licensing agreement was that with only 350 employees, Gilead still did not yet have the capability to sell its drugs directly to overseas buyers. Shultz. [93], Gilead has also been accused of price-gouging on other medications developed with public funding, including AIDS PrEP drug Tenofovir and hepatitis C drug sofosbuvir as well as Remdesivir. 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